ANTIBIOTIC RESISTANCE OF ISOLATED STRAINS OF MICROORGANISMS IN PATIENTS HOSPITALIZED FOR SURGICAL TREATMENT AT THE UROLOGY CLINIC UMBAL BURGAS OVER A FIVE-YEAR PERIOD, Zlatka Cholakova, Nikolay Mirinchev

Abstract: Antibiotic resistance is a significant challenge in the treatment of urological infections,
increasing the risk of therapeutic failure and prolonging hospital stays. This study analyzes the
resistance patterns of bacterial strains isolated from patients undergoing urological surgeries
(2019–2023).

A total of 3,927 patients were examined, with 1,227 undergoing microbiological testing. Among
513 positive samples, 30 bacterial strains were identified. The highest number of positive
samples (431 out of 1,068) were found in urine. The most frequently isolated microorganisms
were from the Enterobacteriaceae, Pseudomonadaceae, and Staphylococcaceae families, with
Pseudomonas aeruginosa showing significant resistance.
The results highlight the need to update therapeutic regimens based on the local resistance
profile and enforce stricter control over antibiotic use. Candida albicans and Proteus vulgaris
remain susceptible to standard therapies.

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